Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00469Cinacalcet hydrochloride--
BADD_D00471Ciprofloxacin0.000090%
BADD_D00474Cisplatin0.011456%
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00479Cladribine0.001095%
BADD_D00480Clarithromycin--
BADD_D00487Clindamycin phosphate--
BADD_D00488Clobazam--
BADD_D00495Clofarabine--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam--
BADD_D00502Clonidine--
BADD_D00504Clopidogrel--
BADD_D00511Clozapine--
BADD_D00519Colesevelam hydrochloride--
BADD_D00524Colistimethate sodium--
BADD_D00528Conjugated estrogens--
BADD_D00533Cortisone acetate0.010733%
BADD_D00535Crizotinib0.012788%
BADD_D00536Crofelemer--
BADD_D00537Cromoglycate--
BADD_D00544Cyclo-upup--
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine--
BADD_D00554Cyproterone--
BADD_D00555Cyproterone acetate--
BADD_D00560Cytarabine--
BADD_D00561Cytarabine hydrochloride--
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